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Medullary carcinoma

Last reviewed dd mmm yyyy. Last edited dd mmm yyyy

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Medullary carcinoma is a histologically characteristic form of invasive ductal breast carcinoma. It constitues about 4-5% of all invasive breast cancers. Compared to other breast carcinomas, they tend to metastasize to lymph nodes much less readily.

Macroscopic features include:

  • relatively larger than ductal NOS (up to 10cm)
  • consistency soft and fleshy
  • well-circumscribed
  • smooth surface

Histologically, they are characterised by:

  • little stroma
  • cells growing in irregular sheets
  • lymphocytic infiltrate - response may contribute to its relatively better prognosis
  • occasionally glandular patterns - medullary adenocarcinoma

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The content herein is provided for informational purposes and does not replace the need to apply professional clinical judgement when diagnosing or treating any medical condition. A licensed medical practitioner should be consulted for diagnosis and treatment of any and all medical conditions.

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