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Clinical features

Last reviewed dd mmm yyyy. Last edited dd mmm yyyy

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LGMD is a clinically heterogeneous disease, from a mild late onset form to severe and even congenital forms.

LGMD is characterised by:

  • progressive symmetrical atrophy and weakness of the musccles of:
    • proximal limbs
    • shoulder and pelvic girdles
    • trunk muscles
  • the facial muscles are spared

Onset of symptoms is usually during the first two decades of life. Patients are usually confined to a wheelchair within 10-20 yr.

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The content herein is provided for informational purposes and does not replace the need to apply professional clinical judgement when diagnosing or treating any medical condition. A licensed medical practitioner should be consulted for diagnosis and treatment of any and all medical conditions.

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