Clinical features include:
In the acute setting, features of sepsis such as irritability and poor handling should be sought.
The most important distinction to make is between a paralytic and non-paralytic cause. A useful discriminating clinical test is to hold the baby in a ventral position; a baby with a paralytic cause of floppiness shows much less movement than a baby with non-paralytic floppiness.
The baby should be carefully examined for any dysmorphology.
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