NICE state with respect to use of fresh frozen plasma (1)
Thresholds and targets
Fresh frozen plasma transfusion for patients should only be considered with clinically significant bleeding but without major haemorrhage if they have abnormal coagulation test results (for example, prothrombin time ratio or activated partial thromboplastin time ratio above 1.5).
Do not offer fresh frozen plasma transfusions to correct abnormal coagulation in patients who:
Consider prophylactic fresh frozen plasma transfusions for patients with abnormal coagulation who are having invasive procedures or surgery with a risk of clinically significant bleeding.
Notes:
Reference:
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