This is a direct test of pancreatic function in which duodenal contents are collected for two hours following a meal containing carbohydrate, protein and fat.
Low enzymic activity - amylase, trypsin or lipase - indicates pancreatic insufficiency.
It is less informative than the secretin / CCK-PZ test because it does not differentiate between a decreased pancreatic response due to a reduced ability to secrete, or a reduced ability to transfer the stimulus, neurally or hormonally.
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