Infection with Epstein-Barr virus (EBV) produces jaundice in 10-15% of cases. Hepatomegaly may be accompanied by pharyngitis, lymphadenopathy and splenomegaly.
Diagnosis is confirmed by atypical blood lymphocytes and a positive monospot test. Note that a monospot test may be falsely positive in hepatitis A infection.
Chronic liver disease does not occur.
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