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Digoxin and St John's wort

Last reviewed dd mmm yyyy. Last edited dd mmm yyyy

Authoring team

St John's wort interacts with digoxin and may lead to reduced digoxin levels.

Suggested management schedule of patient already taking St John's wort:

  • check digoxin level and stop St John's wort

  • note that there may be a rise in digoxin levels on stopping St John's wort

  • it may be necessary to adjust the digoxin dose

Reference:

  • CEM/CMO/2000/4

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