This site is intended for healthcare professionals

Sign in
Go to /sign-in page

You can view 5 more pages before signing in

Granuloma

Last reviewed dd mmm yyyy. Last edited dd mmm yyyy

Authoring team

A granuloma - plural granulomas or granulomata - is a discrete region of granulomatous inflammation defined by its histology after biopsy:

  • epitheloid cells at its centre
  • fusion of epitheloid cells to form a foreign body giant cell - the key feature

There may also be:

  • lymphocyte mantle surrounding epitheloid cells
  • evidence of aetiological agent e.g. tuberculosis bacillus
  • fibroblast proliferation with or without fibrin deposition
  • plasma cells
  • less frequently, neutrophils

A tuberculous granuloma is termed a tubercle. Rheumatoid nodules of rheumatoid arthritis contain granulomas.

The causes of granulomas are detailed under granulomatous inflammation in the submenu.

Related pages

Create an account to add page annotations

Create a free account

Annotations allow you to add information to this page that would be handy to have on hand during a consultation. E.g. a website or number. This information will always show when you visit this page.

The content herein is provided for informational purposes and does not replace the need to apply professional clinical judgement when diagnosing or treating any medical condition. A licensed medical practitioner should be consulted for diagnosis and treatment of any and all medical conditions.

Connect

Copyright 2024 Oxbridge Solutions Limited, a subsidiary of OmniaMed Communications Limited. All rights reserved. Any distribution or duplication of the information contained herein is strictly prohibited. Oxbridge Solutions receives funding from advertising but maintains editorial independence.