This site is intended for healthcare professionals

Sign in
Go to /sign-in page

You can view 5 more pages before signing in

High intensity versus intermediate intensity versus low intensity statin treatment (statins)

Last reviewed dd mmm yyyy. Last edited dd mmm yyyy

Authoring team

Dose of particular statin versus reduction in LDL cholesterol

Dose (mg/day)

5

10

20

40

80

fluvastatin

-

-

21% a

27% a

33% b

pravastatin

-

20% a

24% a

29% a

-

simvastatin

-

27% a

32% b

37% b

42% c,d

atorvastatin

-

37% b

43% c

49% c

55% c

rosuvastatin

38% b

43% c

48% c

53% c

-

  • a 20%- 30%: low intensity

  • b 31%- 40%: medium intensity

  • c Above 40%: high intensity

  • d Advice from the MHRA: there is an increased risk of myopathy associated with high-dose (80 mg) simvastatin. The 80 mg dose should be considered only in patients with severe hypercholesterolaemia and high risk of cardiovascular complications who have not achieved their treatment goals on lower doses, when the benefits are expected to outweigh the potential risks.

Reference:

Related pages

Create an account to add page annotations

Create a free account

Annotations allow you to add information to this page that would be handy to have on hand during a consultation. E.g. a website or number. This information will always show when you visit this page.

The content herein is provided for informational purposes and does not replace the need to apply professional clinical judgement when diagnosing or treating any medical condition. A licensed medical practitioner should be consulted for diagnosis and treatment of any and all medical conditions.

Connect

Copyright 2024 Oxbridge Solutions Limited, a subsidiary of OmniaMed Communications Limited. All rights reserved. Any distribution or duplication of the information contained herein is strictly prohibited. Oxbridge Solutions receives funding from advertising but maintains editorial independence.