Description and relationship between polyneuropathy disability (PND) scores and familial amyloidotic polyneuropathy (FAP) stages
PND score | PND score description | FAP stage | FAP stage description |
0 | No impairment | 0 | No symptoms |
I | Sensory disturbances, preserved walking capability | 1 | Unimpaired ambulation; mostly mild sensory and motor neuropathy in the lower limbs |
II | Impaired walking capability but ability to walk without a stick or crutches | 2 | Assistance with ambulation needed; mostly moderate impairment progression to the lower limbs, upper limbs and trunk |
IIa | Walking only with the help of 1 stick or crutch | 2 | Assistance with ambulation needed; mostly moderate impairment progression to the lower limbs, upper limbs and trunk |
IIIb | Walking with the help of 2 sticks or crutches | 2 | Assistance with ambulation needed; mostly moderate impairment progression to the lower limbs, upper limbs and trunk |
IV | Confined to a wheelchair or bedridden | 3 | Wheelchair-bound or bedridden; severe sensory and motor neuropathy of all limbs |
Abbreviations: FAP, familial amyloidotic polyneuropathy; PND, polyneuropathy disability
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