Abdominal pain with weight loss (unexplained), 40 and over) - urgent cancer referral guidance
Symptom and Specific Features  | Possible Cancer  | Recommendation  | 
Abdominal pain with weight loss (unexplained), 40 and over)  | Colorectal  | Refer people using a suspected cancer pathway referral (for an appointment within 2 weeks)  | 
Symptom and Specific Features  | Possible Cancer  | Recommendation  | 
Abdominal pain (unexplained) with rectal bleeding in adults under 50)  | Colorectal  | Consider a suspected cancer pathway referral (for an appointment within 2 weeks)  | 
Symptom and Specific Features  | Possible Cancer  | Recommendation  | 
Abdominal pain without rectal bleeding, 50 and over  | Colorectal  | Offer testing for occult blood in faeces (faecal immunochemical testing) Check FBC  | 
Upper abdominal pain - urgent cancer referral guidance
Symptom and Specific Features  | Possible Cancer  | Recommendation  | 
Upper abdominal pain with weight loss, 55 and over  | Stomach or oesophageal  | Offer urgent direct access upper gastrointestinal endoscopy (to be performed within 2 weeks)  | 
Symptom and Specific Features  | Possible Cancer  | Recommendation  | 
Upper abdominal pain with low haemoglobin levels or raised platelet count or nausea or vomiting, 55 and over  | Oesophageal or stomach  | Consider non-urgent direct access upper gastrointestinal endoscopy  | 
Abdominal or pelvic pain (persistent or frequent - particularly more than 12 times per month) in women, especially if 50 and over
Symptom and Specific Features  | Possible Cancer  | Recommendation  | 
Abdominal or pelvic pain (persistent or frequent - particularly more than 12 times per month) in women, especially if 50 and over  | Ovarian  | Measure Ca-125  | 
Abdominal pain with weight loss, 60 and over
Symptom and Specific Features  | Possible Cancer  | Recommendation  | 
Abdominal pain with weight loss, 60 and over  | Pancreatic  | Consider an urgent direct access CT scan (to be performed within 2 weeks), or an urgent ultrasound scan if CT is not available  | 
Irritable bowel syndrome symptoms within the last 12 months in women 50 and over
Symptom and Specific Features  | Possible Cancer  | Recommendation  | 
Irritable bowel syndrome symptoms within the last 12 months in women 50 and over  | Ovarian  | Carry out appropriate tests for ovarian cancer, because irritable bowel syndrome rarely presents for the first time in women of this age Measure serum CA125 in primary care  | 
Reference:
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