Systemic inflammatory response syndrome (SIRS)
Systemic inflammatory response syndrome (SIRS)
- defined as 2 or more of the following variables:
- fever of more than 38°C (100.4°F) or less than 36°C (96.8°F)
- heart rate of more than 90 beats per minute
- respiratory rate of more than 20 breaths per minute or arterial carbon dioxide tension (PaCO 2) of less than 32 mm Hg
- abnormal white blood cell count (>12,000/µL or < 4,000/µL or >10% immature [band] forms)
- fever of more than 38°C (100.4°F) or less than 36°C (96.8°F)
SIRS is nonspecific
- not always related to infection - can be caused by ischaemia, inflammation, trauma, infection, or several insults combined
Reference
- Kaukonen KM, Bailey M, Pilcher D, Cooper DJ, Bellomo R. Systemic inflammatory response syndrome criteria in defining severe sepsis. N Engl J Med. 2015 Apr 23;372(17):1629-38
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