Pathology
Muscular, medium-sized arteries are involved throughout the skin and most viscera.
There is inflammation of all layers of the vessel wall with fibrinoid necrosis and inflammatory cell infiltrates. (1)
Tissue damage is due to ischaemia caused by:
- acute thrombosis of the inflamed artery
- arterial stenosis due to fibrosis
The vasculitis may be due to deposition of immune complexes in the vessel wall.
1. Polyarteritis Nodosa - a contemporary overview. U.S. National Library of Medicine 2016. Available from: https://pubmed.ncbi.nlm.nih.gov/26884100/
Create an account to add page annotations
Annotations allow you to add information to this page that would be handy to have on hand during a consultation. E.g. a website or number. This information will always show when you visit this page.