Acute extrinsic allergic alveolitis - investigations
The investigation of acute extrinsic allergic alveolitis should include:
- FBC shows neutrophilia with raised or normal eosinophils
- ESR is raised
- blood gases show hypoxaemia
- serum precipitins are present
- chest radiography shows a variable appearance, including ground-glass or nodules
- lung function tests demonstrate a transient, slight reduction in lung volume and a transient reduction in transfer factor
- bronchoalveolar lavage shows a predominance of mast cells and lymphocytes
- provocation test with suspected antigen if the history is unclear
- transbronchial or open lung biopsy if the diagnosis is in doubt
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