Clinical features
The clinical manifestations of renal bone disease are non-specific. The most common symptom is bone pain which is mainly in the legs, hips, knees, and lower back.
Other features may include:
- proximal muscle weakness - usually with normal muscle enzyme levels
- skeletal deformities of the spine and limbs - mainly in patients with osteomalacia
- tumoural and periarticular calcifications - causing swelling and acute joint pain
- pruritus - possibly from the high levels of calcium or phosphate in the skin
Reference
- Lafage-Proust M. Bone and Chronic Kidney Disease. Semin Musculoskelet Radiol. 2023 Aug;27(4):463-470.
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