This site is intended for healthcare professionals

CPD
CPD
Pro
Pro
Sign in
Go to /sign-in page

You can view 5 more pages before signing in

Go to /pro/cpd-dashboard page

This page is worth 0.05 CPD credits. CPD dashboard

Go to /account/subscription-details page

This page is worth 0.05 CPD credits. Upgrade to Pro

Pathology

Last reviewed dd mmm yyyy. Last edited dd mmm yyyy

Authoring team

Most cases of haemolytic uraemic syndrome are associated with diarrhoea and occur in children. These cases, in general, have a natural history where there is complete recovery and there is usually no renal biopsy taken.

Diarrhoea-associated HUS characterised by:

  • glomerular capillary thrombosis
  • some arteriolar thrombosis and necrosis

Idiopathic HUS:

  • generally occurs in adults
  • show a preglomerular pathology with intimal proliferation and luminal stenosis affecting arterioles and small arteries
  • in 10% of adult cases there are no pathological changes seen in the glomeruli or vessels and the only lesion seen is acute tubular necrosis (1)

Reference:

  • (1) Neild GH (1993). Haemolytic uraemic syndrome in practice. Lancet, 343, 398-402.

Create an account to add page annotations

Create a free account

Annotations allow you to add information to this page that would be handy to have on hand during a consultation. E.g. a website or number. This information will always show when you visit this page.

The content herein is provided for informational purposes and does not replace the need to apply professional clinical judgement when diagnosing or treating any medical condition. A licensed medical practitioner should be consulted for diagnosis and treatment of any and all medical conditions.

Connect

Copyright 2024 Oxbridge Solutions Limited, a subsidiary of OmniaMed Communications Limited. All rights reserved. Any distribution or duplication of the information contained herein is strictly prohibited. Oxbridge Solutions receives funding from advertising but maintains editorial independence.