Aetiology
The common aetiological factor in all forms of osteopetrosis is a defect in osteoclast activity. Invariably there is reduced bone resorption; occasionally excess bone deposition is also present.
Histologically the osteoclasts are numerous and exceptionally large.
Reference
- Del Fattore A, Cappariello A, Teti A; Genetics, pathogenesis and complications of osteopetrosis. Bone. 2008 Jan;42(1):19-29.
Create an account to add page annotations
Annotations allow you to add information to this page that would be handy to have on hand during a consultation. E.g. a website or number. This information will always show when you visit this page.