Epidemiology
Epidemiology:
- in England, obstetric cholestasis (also referred to as intrahepatic cholestasis of pregnancy) affects 0.7% of pregnancies in multi-ethnic populations and 1.2–1.5% of women of Indian–Asian or Pakistani–Asian origin
- prevalence is influenced by genetic and environmental factors and varies between populations worldwide
- for example, in Chile,2.4% of all pregnancies are affected, with a 5% prevalence in women of Araucanian–Indian origin
Reference:
- Walker KF et al. Pharmacological interventions for treating intrahepatic cholestasis of pregnancy. Cochrane Database of Systematic Reviews 2020, Issue 7. Art. No.: CD000493. DOI: 10.1002/14651858.CD000493.pub3.
- Royal College of Obstetricians and Gynaecologists. Intrahepatic cholestasis of pregnancy (Green-top Guideline No. 43). Published August 2022
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