Diagnosis
The clinical features of aplastic anaemia are non-specific. Diagnosis is based upon:
- peripheral blood:
- neutrophils less than 0.5 x 10^9 per litre
- platelets less than 20 x 10^9 per litre
- reticulocyte count corrected for haematocrit less than 1%
- marrow:
- severe hypocellularity
- moderate hypocellularity with < 30% of residual cells being haematopoietic
At least two peripheral plus one marrow criteria must be satisfied.
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