Assessing anticoagulation control with vitamin K antagonists
Assessing anticoagulation control with vitamin K antagonists
- calculate the person's time in therapeutic range (TTR) at each visit. When calculating TTR:
- use a validated method of measurement such as the Rosendaal method for computer-assisted dosing or proportion of tests in range for manual dosing
- exclude measurements taken during the first 6 weeks of treatment
- calculate TTR over a maintenance period of at least 6 months
Reassess anticoagulation for a person with poor anticoagulation control shown by any of the following:
- 2 INR values higher than 5 or 1 INR value higher than 8 within the past 6 months
- 2 INR values less than 1.5 within the past 6 months
- TTR less than 65%
Reference:
- NICE. Atrial fibrillation: diagnosis and management. NICE guideline NG196. Published April 2021, last updated June 2021
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