Epidemiology
- affects 6-10/1000 of the UK population (1)
- most commonly affects middle-aged women
- female to male ratio is 9:1
- association with HLA-B8, HLA-DR3, HLA-DRW52
- affects 50% of patients with rheumatoid arthritis
- affects 30% of patients with other autoimmune diseases
- slowly progressive disease
Reference:
- (1) Arthritis Research Campaign (2000). Rheumatic Disease In Practice, September 2000, 3.
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