Meta-analysis of St John's wort in depression
- a meta-analysis of 27 trials comparing St John's wort with either placebo or active treatments was undertaken
- this analysis suggests that St. John's wort is more effective than placebo and is as effective as low-dose tricyclic antidepressants (TCAs) as an antidepressant therapy
- the mechanism of action appears to be the inhibition of the reuptake of noramines
Reference:
- 1) EBM (1999), 4(3), 82.
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