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Triptans and St John's wort

Authoring team

St John's wort (SJW) interacts with triptans (sumatriptan, naratriptan, rizatriptan, zolmitriptan) and may lead to increased serotonergic effects with an increased incidence of adverse reactions.

If a patient is taking SJW and triptans it is advised that the patient stops taking SJW.

Reference:

  • CEM/CMO/2000/4

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