Theophylline and St John's wort
St John's wort (SJW) interacts with theophylline and may cause reduced theophylline levels.
Suggested management of patients already taking SJW preparations:
- check theophylline levels and stop SJW
- note that there may be an increase in theophylline levels on stopping SJW
- it may be necessary to adjust the theophylline dose
Reference:
- CEM/CMO/2000/4
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