Patients are frequently asymptomatic.
In others, presentation may be with features such as:
- mild hypertension
- lethargy
- muscular weakness
- polyuria and polydipsia
- persistent hypokalaemia
- intermittent paraesthesiae, tetany and occasionally paralysis
There is an increasing frequency in the diagnosis of primary aldosteronism (1):
- principal reason for the increasingly frequent diagnosis of this disease, once viewed as rare, is that normokalemic Conn's syndrome is now recognized as an independent disease entity
- normal serum potassium may be present in up to 38% of patients, especially in patients with adrenal hyperplasia or familial aldosteronism
- found in 5% to 18% of patients with high blood pressure
Reference:
- Aronova A, Fahey TJ III, Zarnegar R. Management of hypertension in primary aldosteronism. World J Cardiol. 2014 May 26;6(5):227-33