Hypervolaemic hyponatraemia
- clinically detectable increased ECF volume plus hyponatraemia - generally reflects hypervolaemia from some degree of body Na+ excess
- hyponatraemia with ECF volume excess can arise in a variety of diseases
- causes of hypervolaemic hyponatraemia include:
- CHF
- liver cirrhosis
- nephrotic syndrome
- renal failure
- excessive water intake
- volume excess is generally diagnosed clinically from the history, physical examination and laboratory results
- patients with clinical signs of volume overload (subcutaneous oedema, ascites, pulmonary oedema)
- should be considered to have hypervolaemia unless there are alternative explanations for these findings
- patients with clinical signs of volume overload (subcutaneous oedema, ascites, pulmonary oedema)
- causes of hypervolaemic hyponatraemia include:
Reference:
- Adrogué HJ, Tucker BM, Madias NE. Diagnosis and management of hyponatremia: a review. JAMA. 2022 Jul 19;328(3):280-91
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