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Investigations

Last reviewed dd mmm yyyy. Last edited dd mmm yyyy

Authoring team

Initial investigation - measurement of fasting cholesterol and triglyceride levels. In this procedure the patient follows his normal diet for the 2 weeks preceding the test and any drugs that may affect lipid metabolism are withdrawn. Note also that the results obtained may be influenced by acute illness and the test should not be performed in period from 24 hrs to 6 months following major stress e.g. MI.

A more detailed lipid profile investigation provides more information (total cholesterol, HDL-cholesterol, triglycerides, Total cholesterol:HDL-cholesterol ratio).

Examination of stored serum

  • raised VLDL - causes a diffuse milky appearance
  • chylomicronaemia - creamy upper layer with clear plasma underneath

Investigations to exclude secondary causes of hyperlipidaemia - FBC, ESR, LFTs, TFTs, g


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The content herein is provided for informational purposes and does not replace the need to apply professional clinical judgement when diagnosing or treating any medical condition. A licensed medical practitioner should be consulted for diagnosis and treatment of any and all medical conditions.

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