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Non-union of fracture

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This is the failure to achieve bony healing at a fracture site - the medullary cavity of the fragments have closed with the fragments separate.

The most widely accepted definition of non-union is a fracture that persists for at least 9 months without signs of healing for 3 months. This is a loose definition, as not every bone behaves the same, and that the use of medicines like bisphosphonates can affect healing time.

Reference

  1. Cunningham BP, Brazina S, Morshed S, Miclau T. Fracture healing: A review of clinical, imaging and laboratory diagnostic options. Injury. 2017 Jun;48 Suppl 1:S69-S75.

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