The nerves supplying the oesophagus are dependent on position; they are all autonomic:
- cervical oesophagus:
- recurrent laryngeal nerve branches
 - cervical sympathetic trunks from the middle cervical ganglion and running with the inferior thyroid arteries
 
 - thoracic oesophagus:
- vagus: both vagal trunks and oesophageal plexus
 - sympathetic trunks
 - greater splanchnic nerves
 
 - inferior oesophagus:
- vagal trunks
 - oesophageal plexuses
 - thoracic sympathetic trunks
 - greater splanchnic nerve; occasionally, the lesser splanchnic nerve
 
 
These fibres communicate with plexuses within the wall of the oesophagus:
- myenteric plexus, between the outer muscular layers of the wall
 - Meissner's plexus, submucosal
 
The nuclei for nerves to the oesophagus are located in:
- nucleus ambiguus: for vagal fibres to upper skeletal muscle
 - dorsal motor nucleus: for vagal fibres to inferior smooth muscle
 - inferior salivary nucleus: vagal fibres to glands
 - inferior vagal ganglion: pain fibres