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Investigations

Authoring team

Investigations in acute disseminated encephalomyelitis show:

  • CSF - pleocytosis, lymphocytic and often, nucleophilic; raised protein; oligoclonal bands are present initially but then disappear
  • blood - normal or evidence of neutrophilia, lymphocytosis or lymphopenia
  • EEG - shows diffuse slow wave activity
  • CT - normal
  • MRI - shows small focal white matter changes, usually, symmetrical. The plaques may become haemorrhagic and oedematous, and present as mass lesions.

Reference

  1. Li K et al. Clinical Presentation and Outcomes of Acute Disseminated Encephalomyelitis in Adults Worldwide: Systematic Review and Meta-Analysis. Front Immunol. 2022;13:870867

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