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Clinical features

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Typically, a sebaceous carcinoma presents as a yellow, ulcerated nodule on the face - particularly the eyelids - or scalp. Eyelid lesions are more likely to present with clinical metastases.

Alternatively, sebaceous carcinoma can present as a pedunculated lesion, irregular mass, or diffusely thickened skin. Notably, approximately 75% of these cases occur in the periocular region, with the upper eyelid 2 to 3 times more frequently involved than the lower eyelid.

It may be associated with a variety of other skin tumours in Muir-Torre Syndrome.

Reference

  1. Papadimitriou I et al. Sebaceous Neoplasms. Diagnostics (Basel). 2023 May 09;13(10)

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