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Ehrlich's reagent

Last reviewed dd mmm yyyy. Last edited dd mmm yyyy

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Ehrlich's aldehyde test is used to confirm a diagnosis of acute intermittent porphyria.

Ehlich's aldehyde reagent consists of p-dimethyl amino benzaldehyde in acid solution.

Equal volumes of urine and Ehrlich's reagent are mixed. If a pink colour is formed this indicates a raised urinary concentration of either porphobilinogen or urobilinogen.

In cases of raised porphobilinogen, as in acute intermittent porphyria, the pink precipitate is observed to be insoluble in chloroform.

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